Buku sediaan galenik4/3/2023 Results: The results show that many cytotoxic agents have been developed in nanocapsules systems due to their low water solubility, chemical instability, and low bioavailability. Methods: The study was performed by systematic literature review using selected articles from reputable databases that meet the inclusion and exclusion criteria. Objective: This research was conducted to determine the type of polymers for nanoencapsulation of cytotoxic agents and analyze the effect of nanoencapsulation on the cytotoxic activity. Nanoencapsulation, a part of nanotechnology, was known can be involved in cytotoxic agents. Modification on drug delivery systems based on nanotechnology was applied to improve the effectiveness and safety of treatment. Background: The incidence and mortality of cancer are rapidly growing worldwide.
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